Opportunity Information: Apply for RFA AT 24 005
The NIH is soliciting applications for an R24 research resource grant titled "Research Resource for Systematic Reviews of Complementary and Integrative Health (Clinical Trial Not Allowed)" under opportunity number RFA-AT-24-005 (CFDA 93.213). The overall purpose is to fund an infrastructure-style resource that supports evidence synthesis in complementary and integrative health by sustaining and improving a database of controlled trials. Rather than funding new clinical studies, this award is focused on organizing, curating, and continuously updating the research evidence base so that systematic reviewers, researchers, clinicians, policy makers, and the public can more easily find and use high-quality information about complementary and integrative health interventions.
A central expectation is that the funded team will operate a reliable database of controlled trials of complementary and integrative health interventions. Applicants are expected to clearly explain their plan to either build a database from the ground up, maintain an existing database, or convert an existing database into a form that better serves systematic review needs. The application should spell out practical details such as how studies will be identified and screened, what data elements will be captured, how records will be structured and indexed, what quality control procedures will be used, and how updates will be handled over the full period of the award. Just as important, the team needs to describe how the database will be kept current, including ongoing surveillance of the literature and an update workflow that prevents the resource from becoming outdated.
Beyond simply housing trial records, the initiative emphasizes broader reach and usability. The resource is expected to increase outreach, access, and availability to a wider scientific community, as well as to public audiences and policy makers. In practice, this means the award is not only about technical database management, but also about dissemination and user engagement. Strong proposals would typically address how users will discover the resource, how the interface and outputs will support different audiences, what forms of access will be provided (for example, searchable web access and downloadable exports), and how the team will promote adoption and appropriate use of the database in systematic reviews and evidence-informed decision making.
The opportunity also requires active evidence synthesis work in addition to database maintenance. The funded resource should update multiple systematic reviews with current evidence and conduct new systematic reviews each year. Review topics must align with NCCIH priorities as described in the NCCIH Strategic Plan 2021-2025, with special emphasis on whole person research and multi-component complementary and integrative health interventions. Within a whole person health framework, the NIH is particularly interested in topics that examine interconnected biological and behavioral systems, evaluate multicomponent intervention packages or therapeutic systems, and assess outcomes that span multiple organs or systems rather than focusing narrowly on a single endpoint. The intent is to support systematic reviews that are methodologically rigorous and relevant to how complementary and integrative approaches are often delivered in real-world settings.
Eligibility is broad and includes many types of U.S.-based organizations: state, county, and local governments; special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education where specified); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI), along with faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. Foreign organizations and foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible. However, foreign components are allowed when they meet the NIH definition under the NIH Grants Policy Statement, which typically means specific, well-justified international elements can be included within an otherwise eligible U.S. application.
Administratively, this is a discretionary grant mechanism using the NIH R24 activity code, and it is explicitly labeled "Clinical Trial Not Allowed," reinforcing that the work should center on research resources and systematic review activities rather than initiating clinical trials. The opportunity was created on July 13, 2023, with an original closing date of August 31, 2023, according to the source information provided. Award ceiling and expected number of awards are not specified in the provided listing, so applicants would normally look to the full NIH notice and related budget guidance for details on funding levels and project period expectations.Apply for RFA AT 24 005
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Resource for Systematic Reviews of Complementary and Integrative Health (R24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213.
- This funding opportunity was created on 2023-07-13.
- Applicants must submit their applications by 2023-08-31. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Single Source: Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Data Coordinating Center (U24- Clinical Trial Not Allowed) Apply for RFA HL 24 007 Funding Number: RFA HL 24 007 Agency: National Institutes of Health Category: Health Funding Amount: $1,260,000 |
| Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Research Centers (U01 Clinical Trial Not Allowed) Apply for RFA HL 24 006 Funding Number: RFA HL 24 006 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Single Source: Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Human Tissue Core (U01- Clinical Trial Not Allowed) Apply for RFA HL 24 012 Funding Number: RFA HL 24 012 Agency: National Institutes of Health Category: Health Funding Amount: $300,000 |
| Health Equity and the Cost of Novel Treatments for Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Not Allowed) Apply for RFA AG 24 050 Funding Number: RFA AG 24 050 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Rural Hospital Stabilization Pilot Program Apply for HRSA 24 082 Funding Number: HRSA 24 082 Agency: Health Resources and Services Administration Category: Health Funding Amount: $4,000,000 |
| Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional) Apply for PAR 23 238 Funding Number: PAR 23 238 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional) Apply for PAR 23 239 Funding Number: PAR 23 239 Agency: National Institutes of Health Category: Health Funding Amount: $275,000 |
| The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R34 Clinical Trial Optional) Apply for RFA HL 24 009 Funding Number: RFA HL 24 009 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R01 Clinical Trial Optional) Apply for RFA HL 24 008 Funding Number: RFA HL 24 008 Agency: National Institutes of Health Category: Health Funding Amount: $420,000 |
| Pharmacokinetic and Pharmacodynamic (PK/PD) Studies of mTOR Inhibitors on Aging-Related Indications (U01 Clinical Trial Required) Apply for RFA AG 24 044 Funding Number: RFA AG 24 044 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed) Apply for RFA RM 23 015 Funding Number: RFA RM 23 015 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Supporting Vaccine Confidence Apply for NV VSR 24 001 Funding Number: NV VSR 24 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $250,000 |
| Role of Environmental Stress in the Health Inequities of Alzheimer's Disease-Related Dementias (ADRD) (R01 - Clinical Trial Not Allowed) Apply for RFA NS 24 024 Funding Number: RFA NS 24 024 Agency: National Institutes of Health Category: Health Funding Amount: $499,999 |
| National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional) Apply for PAR 23 235 Funding Number: PAR 23 235 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Network of Genomics-Enabled Learning Health Systems (gLHS) Coordinating Center (U01 Clinical Trials Required) Apply for RFA HG 23 042 Funding Number: RFA HG 23 042 Agency: National Institutes of Health Category: Health Funding Amount: $900,000 |
| Network of Genomics-Enabled Learning Health Systems (gLHS) Clinical Sites (U01 Clinical Trial Required) Apply for RFA HG 23 041 Funding Number: RFA HG 23 041 Agency: National Institutes of Health Category: Health Funding Amount: $450,000 |
| Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed) Apply for PAR 23 240 Funding Number: PAR 23 240 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Public Health Communication Messaging about the Continuum of Risk for Tobacco Products (U01 Clinical Trial Required) Apply for RFA OD 23 021 Funding Number: RFA OD 23 021 Agency: National Institutes of Health Category: Health Funding Amount: $2,500,000 |
| Validating digital health technologies for monitoring biomarkers in ADRD clinical trials (R61/R33 - Clinical Trials Optional) Apply for RFA NS 24 026 Funding Number: RFA NS 24 026 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Alcohol Health Services Research (R34 Clinical Trial Optional) Apply for PAR 23 252 Funding Number: PAR 23 252 Agency: National Institutes of Health Category: Health Funding Amount: $450,000 |
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